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	<title>supplement-truths-blog.com &#187; negative drug studies</title>
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		<title>Negative Antidepressant Drug Trials Tucked Quietly Away</title>
		<link>http://blog.nutritional-supplement-truths.com/negative-antidepressant-drug-trials-tucked-quietly-away/</link>
		<comments>http://blog.nutritional-supplement-truths.com/negative-antidepressant-drug-trials-tucked-quietly-away/#comments</comments>
		<pubDate>Tue, 27 May 2008 02:49:32 +0000</pubDate>
		<dc:creator>Brett</dc:creator>
				<category><![CDATA[General Health]]></category>
		<category><![CDATA[antidepressant]]></category>
		<category><![CDATA[big pharma]]></category>
		<category><![CDATA[doctors]]></category>
		<category><![CDATA[file drawer effect]]></category>
		<category><![CDATA[health]]></category>
		<category><![CDATA[longevity]]></category>
		<category><![CDATA[negative drug studies]]></category>
		<category><![CDATA[pharmaceutical]]></category>
		<category><![CDATA[supplement]]></category>

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		<description><![CDATA[Last week I posted an entry about the negative [tag-tec]supplement[/tag-tec] report released last month in the Harvard Men&#8217;s Health Watch newsletter. In that post I made mention of the fact that over the years there has been research and studies released which have “been &#8216;sponsored&#8217; by those with &#8216;anti-supplement vested interests&#8217;, such as Big Pharma, [...]]]></description>
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<p style="margin-bottom: 0in"><span>Last week I posted an entry about the negative [tag-tec]supplement[/tag-tec] report released last month in the  </span><em><span><em>Harvard Men&#8217;s Health Watch</em> </span></em><span>newsletter.</span></p>
<p style="margin-bottom: 0in"><span>In that post  I made mention of the fact that over the years there has been research and studies released which have “been <strong>&#8216;sponsored&#8217; </strong>by those with<strong> &#8216;anti-supplement vested interests&#8217;, </strong>such as  <strong>Big Pharma, </strong>where the final conclusion has been<strong> pre-determined before the study even begins!”</strong></span></p>
<p style="margin-bottom: 0in">So today I thought I would tell you about another NASTY behavior of pharmaceutical drug companies – <font size="+1">HIDING NEGATIVE DRUG STUDIES!</font></p>
<p style="margin-bottom: 0in"><span id="more-25"></span></p>
<p><em><font color="#07606f"><strong>In January this year researchers reported that almost a third of antidepressant studies are never published (anywhere) and almost all these hidden studies show that the drug being tested did not work!</strong></font></em></p>
<p style="margin-bottom: 0in">This behavior is known as the <strong>“file drawer effect” </strong>and it is believed to have been going on for years.</p>
<p style="margin-bottom: 0in">A research team of the Oregon Health and Science University reported in the New England Journal of Medicine that unfavorable results have also been <strong>altered</strong>  in some studies to make it appear that the drug is more effective than it really is.</p>
<p style="margin-bottom: 0in">This of course has serious and <strong>potentially deadly consequences</strong> for the public because doctors rely on published studies to help guide them in which medicines they prescribe to patients.</p>
<p style="margin-bottom: 0in">The researchers found <font color="#07606f"><strong>74 studies</strong> </font>that were started for the 12 antidepressants and that <strong><font color="#07606f">38</font> produced positive results for the drug they dealt with. It&#8217;s no surprise that <font color="#07606f">37</font> of these were subsequently published. </strong></p>
<p style="margin-bottom: 0in">BUT&#8230;</p>
<p style="margin-bottom: 0in">The<strong> remaining 36 studies showed negative or questionable results </strong>(as assessed by the FDA.)  Of these <font color="#ff0000"><strong>only 3 were published and 11 more were written up and published in a way that conveyed  the outcome that the drug had worked! </strong></font></p>
<p style="margin-bottom: 0in">See what we&#8217;re up against when it comes to the power and influence of greedy pharmaceutical companies!</p>
<p style="margin-bottom: 0in">&nbsp;</p>
<p style="margin-bottom: 0in">As an example:</p>
<p style="margin-bottom: 0in"><strong><u> Antidepressant and                                          Company Name</u></strong></p>
<p style="margin-bottom: 0in">Paxil                                                                                                                                                   GlaxoSmithKline (GSK)</p>
<p style="margin-bottom: 0in"><font color="#ff0000"><strong> 7 negatives studies. 5 never published</strong></font></p>
<p style="margin-bottom: 0in">&nbsp;</p>
<p style="margin-bottom: 0in">Wellbutrin                                                                                                                           GlaxoSmithKline (GSK)</p>
<p style="margin-bottom: 0in"><font color="#ff0000"><strong>3 studies found. 2 were negative. Both never published</strong></font></p>
<p style="margin-bottom: 0in">&nbsp;</p>
<p style="margin-bottom: 0in">Zoloft                                                                                                                        Pfizer</p>
<p style="margin-bottom: 0in"><font color="#ff0000"><strong> 5 studies found. 3 were negative. All 3 never published.</strong></font></p>
<p style="margin-bottom: 0in"><font color="#ff0000"><strong>The FDA concluded that a fourth study was &#8216;questionable&#8217;  and this was written up to make it seem that the drug worked.</strong></font></p>
<p style="margin-bottom: 0in">&nbsp;</p>
<p style="margin-bottom: 0in">So, what did the companies say when they were contacted in reference to this?</p>
<p style="margin-bottom: 0in">GSK said they post the data from ALL studies on the Internet!</p>
<p style="margin-bottom: 0in">Pfizer responded that ALL its drug studies are disclosed within a year.</p>
<p style="margin-bottom: 0in">&nbsp;</p>
<h2 align="center"><font color="#07606f">Do you believe them?</font></h2>
<p style="margin-bottom: 0in">&nbsp;</p>
<p style="margin-bottom: 0in">Let me know your opinion in the comment section below.</p>
<p style="margin-bottom: 0in">&nbsp;</p>
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<p>Are you using an upmarket multi ingredient vitamin supplement? The types of <a href="http://www.nutritional-supplement-truths.com/super-supplements-2.html" target="_new">supplements promoted as super supplements?</a> Do these higher prices give you SUPER ingredients, SUPER efficiency and SUPERIOR value for money? Let&#8217;s find out!</p>
<p style="margin-bottom: 0in"><a href="http://www.nutritional-supplement-truths.com/super-supplements-2.html" target="_new">Just how super are super supplements &#8211; find out here</a></p>
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<p>Good Health Always!</p>
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